Synthesis of Iodomethyl Benzosultams via an Electrochemical Intramolecular Iodoamination/Cyclization of Olefinic Benzenesulfonamides

-trig cyclization pathway. The protocol features operational simplicity and readily available starting materials, providing rapid access to a broad range of substituted sultams. Its generality is further demonstrated by the synthesis of iodomethyl-substituted isoindolones from olefinic benzamides. Gram-scale synthesis and diverse downstream transformations highlight the synthetic utility and potential of this electrochemical strategy for green and practical applications in organic synthesis.