Bigger Molecules Enter Smaller Channels of Zeolites via Inward-Coil-Alike Adaptation

electron microscopy. These findings suggest, for the first time, that beyond the intrinsic flexibility of zeolite frameworks, guest molecules themselves may exhibit an unexpectedly high degree of conformational alternation to facilitate pore entry. Additionally, we demonstrated photophysical alternation of fluorophores as a result of energy state change in response to structure adaptation to various zeolites. Consequently, the fluorescence lifetime serves as a sensitive descriptor of molecular strain, providing a readout of the diverse confined microenvironments within zeolites. This approach establishes a novel strategy for probing pore accessibility and host-guest interactions in microporous materials.