What question did this study set out to answer?

This review aims to evaluate the role of blood eosinophils as a biomarker in the acute management of wheeze in children.

July 29, 2026Exploration of MedicineOpen Access

The role of eosinophils in the management of acute paediatric wheeze: a scoping review

View Full Paper

Ask AI

Bookmark

Authors

Scoping review maps the clinical utility of eosinophils in acute wheeze management for children, suggesting areas for further research.

This review aims to evaluate the role of blood eosinophils as a biomarker in the acute management of wheeze in children.
Scoping review conducted using Joanna Briggs Institute methodology and PRISMA-ScR guidelines.
Data sourced from Medline, Embase, Cochrane Library, and Web of Science, focusing on studies from the past 20 years.
Eight studies (n=855) were included, featuring both observational and randomized controlled trial designs.
BEO reporting varied significantly across studies with no consensus on units or cut-off values.
Limited evidence suggests that higher BEO may improve outcomes with systemic corticosteroids during rhinovirus-associated wheeze.
No studies provided sufficient data to support eosinophil-guided corticosteroid treatment in acute wheeze.

Norman-Bruce et al. (2026) studied this question.

View Full Paper

Ask AI

Bookmark