Review highlights the clinical application of CKiD U25 eGFR equations in young individuals with CKD, indicating their feasibility and effectiveness.
The CKiD U25 eGFR equations estimate glomerular filtration rate (GFR) in individuals aged 1-25 years with mild to moderate chronic kidney disease (CKD). They use age, height, sex, serum creatinine, and cystatin C values to provide creatinine-based, cystatin C-based, and combined estimates of kidney function for children and adolescents. This review gives an overview of the appropriate use cases, strengths, limitations, and supporting evidence for their clinical application.
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Hanken-Arlen et al. (2026) studied this question.
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