Conceptual paper examines the relationship between cells and organisms, suggesting autonomy should not be conflated with possession.
This conceptual paper examines whether organismal integration should be conflated with ontological possession of cells. It proposes that a cell may be materially contained within, functionally dependent on, and developmentally constrained by an organism while retaining a biologically bounded possibility-space not exhausted by its current organismal role. The paper introduces three terms: cellular episode, basal cellular autonomy, and inter-scalar dissociation. Fertilisation, reprogramming, evolutionary transitions in individuality, synthetic multicellular constructs, tumour microenvironment research, and context-dependent malignant phenotype are used as convergent constraints rather than as proof of a new ontology. Cancer is framed as a possible reconfiguration of the relation between cellular autonomy and organismal integration, not simply the acquisition of autonomy. This version records a conceptual baseline reached on 27 July 2026 before systematic study of Michael Levin’s theoretical corpus.Version note: Version 1.0 is intentionally frozen as the pre-Levin conceptual baseline. Any subsequent comparison with Michael Levin’s theoretical corpus will be published separately, without altering the provenance statement preserved in this record.
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Joaquim Santos Albino (2026) studied this question.
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