Outcomes of In-Hospital Ventricular Fibrillation in Children
Key result
Initial ventricular fibrillation or tachycardia in pediatric cardiac arrest was associated with higher survival to hospital discharge than subsequent development (35% vs 11%; OR 2.6, 95% CI 1.2-5.8).
Why the study?
Does the timing of ventricular fibrillation or tachycardia (initial vs subsequent) affect survival to hospital discharge in pediatric patients with in-hospital cardiac arrest?
Population
1005 patients under 18 years of age with in-hospital cardiac arrest from a large, multicenter registry
Comparison
Initial ventricular fibrillation or tachycardia vs Subsequent ventricular fibrillation or…
Design
Cohort
Follow-up
to hospital discharge
Authors
Discussion
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Implication
Initial VF/VT was associated with higher survival than subsequent in pediatric arrest; leaves open whether timing modifies resuscitation outcomes.
Study Design
Type
Observational (n=1,005)
Multicenter
Yes
Structured PICO
Does the timing of ventricular fibrillation or tachycardia (initial vs subsequent) affect survival to hospital discharge in pediatric patients with in-hospital cardiac arrest?
P
Population
1,005 pediatric patients (under 18 years of age) with in-hospital cardiac arrest from a multicenter registry.
E
Exposure
Initial ventricular fibrillation or tachycardia
C
Comparator
Subsequent ventricular fibrillation or tachycardia (developing during CPR) or no ventricular fibrillation or tachycardia
O
Outcome
Survival to hospital dischargehard clinical
Main Result
Odds Ratio: 2.6 (95% CI 1.2–5.8)
Absolute Event Rate: 35% vs 11%
In pediatric in-hospital cardiac arrest, survival is significantly higher when ventricular fibrillation or tachycardia is the initial rhythm compared to when it develops subsequently during CPR.
Cite This Study
Samson et al. (2006) conducted an observational in In-hospital cardiac arrest (n=1,005). Initial ventricular fibrillation or tachycardia vs. Subsequent ventricular fibrillation or tachycardia was evaluated on Survival to hospital discharge (OR 2.6, 95% CI 1.2-5.8). Initial ventricular fibrillation or tachycardia in pediatric cardiac arrest was associated with higher survival to hospital discharge than subsequent development (35% vs 11%; OR 2.6, 95% CI 1.2-5.8).