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Human Primordial Germ Cells Are Specified from Lineage-Primed Progenitors | Synapse

December 1, 2019Cell Reports204 citationsOpen Access

Human Primordial Germ Cells Are Specified from Lineage-Primed Progenitors

DCDi Chen NSNa Sun LHLei Hou

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Resumen

progenitors upstream of PRDM1 to regulate the expression of SOX17. This serves to protect hPGCLCs from crossing the Weismann's barrier to adopt somatic cell fates and, therefore, is an essential mechanism for successfully initiating in vitro gametogenesis.

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Cite This Study

Chen et al. (Sun,) studied this question.

synapsesocial.com/papers/6a69e55302245592faf185d5 https://doi.org/https://doi.org/10.1016/j.celrep.2019.11.083