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Cancer remains a formidable global health challenge, demanding continuous efforts to develop innovative and effective therapeutic strategies. Recently, Schiff base metal complexes (SBMCs) have attracted considerable interest as potential anticancer agents because of their varied chemical properties and promising biological activities. This comprehensive review delves the latest advancements in the use of SBMCs in cancer therapy. It covers the synthesis and characterization of these complexes, their mechanisms of action, and their potential advantages over conventional chemotherapy. Furthermore, the review discusses challenges and future perspectives in utilizing SBMCs to enhance cancer treatment outcomes, paving the way for a more targeted and personalized approach in the fight against cancer. • General introduction about cancer. • Chemistry of Schiff base. • Cisplatin and its derivative used in cancer therapy. • d -block metal complexes as an anticancer drugs. • Current limitations. • Future prospects.
Tyagi et al. (Tue,) studied this question.