Key result
Prior mild-moderate COVID-19 infection was associated with similar left and right ventricular systolic function and atrial peak systolic strain at six months compared with healthy controls.
Why the study?
Little was known about the long-term cardiac effects of COVID-19, with growing concern regarding cardiac sequelae among survivors.
Does prior mild-moderate COVID-19 infection impair long-term cardiac function measured by speckle tracking echocardiography in survivors?
Observational (n=78)
Does prior mild-moderate COVID-19 infection impair long-term cardiac function measured by speckle tracking echocardiography in survivors?
Uncomplicated mild-moderate COVID-19 infection does not appear to cause long-term systolic or diastolic myocardial dysfunction at six months, suggesting routine echocardiographic screening may be unnecessary.
Funding Acknowledgements Type of funding sources: None. 5COVID-19 is a multi-systemic infectious disease. Nearly 20-30% of hospitalized patients have evidence of acute myocardial involvement, portending a poorer prognosis. However, not much is known about the long-term cardiac effects of the disease. Also, there is a growing concern about the cardiac sequelae of COVID-19 among survivors. In this study, we aimed to investigate the long-term cardiac effects in patients with prior mild-moderate COVID-19 infection, using both conventional and speckle tracking echocardiographic imaging modalities. A total number of 58 patients who have been diagnosed with COVID-19 within the previous six months and 20 age-, sex- and risk factor-matched healthy adults were included. All patients underwent a comprehensive echocardiographic examination. Both conventional and two-dimensional speckle tracking echocardiographic measurements were done. Also, serum cardiac biomarkers were obtained on the day of echocardiographic examination. Compared with healthy controls, COVID-19 survivors had similar left and right ventricular systolic function at six months. Also, left and right atrial peak systolic strain values did not differ between the groups. Long-term cardiac sequelae of COVID-19 infection are still widely unknown, resulting in concern among survivors. This study is valuable in putting forth the unaffected systolic and diastolic myocardial function on long-term in uncomplicated COVID-19 cases and may decrease the survivors’ anxiety and the number of unnecessary applications to cardiology clinics. Abstract Figure. Left ventricle strain analysis Abstract Figure. Right ventricle strain analysis
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Akbulut et al. (2022) conducted an observational in Prior mild-moderate COVID-19 infection (n=78). Prior mild-moderate COVID-19 infection vs. Healthy controls was evaluated on Left and right ventricular systolic function and atrial peak systolic strain. Prior mild-moderate COVID-19 infection was associated with similar left and right ventricular systolic function and atrial peak systolic strain at six months compared with healthy controls.
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