Why the study?
Does dietary stimulation of the nitrate-nitrite-NO pathway improve cardiovascular and renal functions in health and disease?
Population
Healthy subjects, hypertensive subjects, and patients with chronic kidney disease
Design
Review
Key result
Dietary stimulation of the nitrate-nitrite-NO pathway lowers blood pressure in healthy individuals, hypertensive subjects, and patients with chronic kidney disease.
Authors
Loading...
May support nitrate supplementation for BP lowering across groups; leaves open large RCTs for cardiorenal outcomes.
Does dietary stimulation of the nitrate-nitrite-NO pathway improve cardiovascular and renal functions in health and disease?
Dietary nitrate supplementation may offer a therapeutic strategy to lower blood pressure and attenuate oxidative stress in cardiorenal disease, though larger clinical trials are needed.
Carlström et al. (2018) conducted a review in Cardiorenal disease. Dietary stimulation of the nitrate-nitrite-NO pathway was evaluated. Dietary stimulation of the nitrate-nitrite-NO pathway lowers blood pressure in healthy individuals, hypertensive subjects, and patients with chronic kidney disease.