Key result
Severe stenosis (OR 3.65), current smoking (OR 2.67), diabetes (OR 1.86), and reduced ejection fraction (OR 1.76) were independent predictors of new native-vessel occlusion in patients with prior CABG.
Why the study?
Data concerning the prevalence and predictors of new-onset chronic total occlusion of native vessels in patients with prior coronary artery bypass grafting are limited.
What are the predictors for new native-vessel occlusion in patients with prior coronary bypass surgery?
Observational (n=354)
No
What are the predictors for new native-vessel occlusion in patients with prior coronary bypass surgery?
Odds Ratio: 3.65 (95% CI 2.55–5.24)
p-value: p=0.01
In patients with prior CABG, current smoking, reduced ejection fraction, severe stenosis, and diabetes mellitus are independent predictors of new native-vessel occlusion, which occurs in over a third of patients.
May inform post-CABG risk stratification; hypothesis-generating for prospective validation.
Objectives . Chronic total occlusion (CTO) is prevalent in patients with prior coronary artery bypass grafting (CABG). However, data available concerning the prevalence of new-onset CTO of native vessels in patients with prior CABG is limited. Therefore, the objective of the study is to determine predictors for new native-vessel occlusion in patients with prior coronary bypass surgery. Methods . 354 patients with prior CABG receiving follow-up angiography are selected and analyzed in the present study, with clinical and angiographic variables being analyzed by logistic regression to determine the predictors of new native-vessel occlusion. Results . The overall new occlusion rate was 35.59%, with multiple CTOs (42.06%) being the most prevalent (LAD 24.60% and RCA 18.25%, respectively). Additionally, current smoking (OR: 2.67; 95% CI: 2.60 to 2.74; p=0.01), reduced ejection fraction (OR: 1.76; 95% CI: 1.04 to 2.97; p=0.04), severe stenosis (OR: 3.65; 95% CI: 2.55 to 5.24; p=0.01), and diabetes mellitus (OR: 1.86; 95% CI: 1.34 to 2.97; p=0.04) serve as the independent predictors for new native-vessel occlusion. Conclusion . As to high incidence of postoperative CTO, appropriate revascularization strategies and postoperative management should be taken into careful consideration.
No takes yet. Share an insight, caveat, or question.
Zheng et al. (2019) conducted an observational in Prior coronary artery bypass grafting (CABG) (n=354). Severe stenosis vs. Absence of severe stenosis was evaluated on New native-vessel occlusion (OR 3.65, 95% CI 2.55-5.24, p=0.01). Severe stenosis (OR 3.65), current smoking (OR 2.67), diabetes (OR 1.86), and reduced ejection fraction (OR 1.76) were independent predictors of new native-vessel occlusion in patients with prior CABG.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: