Key result
Administration of low-molecular-weight heparin in combination with warfarin led to gradual subsidence of clinical symptoms in a 61-year-old man with massive pulmonary embolism.
Case Report (n=1)
This case highlights the importance of recognizing Westermark's sign on chest radiography and S1Q3T3 pattern on ECG for the prompt diagnosis of life-threatening pulmonary embolism.
Supports LMWH plus warfarin for massive PE symptom relief in select cases; leaves open generalizability pending controlled trials.
1016-3190/$ e see front matter Copyright 2012, Bu http://dx.doi.org/10.1016/j.tcmj.2012.08.001 A 61-year-old man with peripheral arterial occlusive disease presented to the hospital with progressive dyspnea and right-side chest pain for 2 months. On arrival, he was in respiratory distress and his initial oxygen saturation was 92% under room air. Chest radiography showed oligemia distal to the right pulmonary trunk (Westermark’s sign; Fig. 1A, arrow). Computed tomography angiography demonstrated a massive pulmonary embolism (PE) trapped in the right pulmonary trunk (Fig. 1B, arrow) with ground glass opacities, suspected to be an impending lung infarction (Fig. 1C, arrow). An electrocardiogram disclosed an S wave in lead I, and a Q wave and inversed T wave in lead III (S1Q3T3 pattern; Fig. 1D). His clinical symptoms subsided gradually after administration of low-molecular-weight heparin in combination with warfarin. PE is a life-threatening and underestimated disease. Clinicians should be very cautious when approaching a patient with dyspnea or chest pain, as PE can result in significant morbidity and mortality if not diagnosed promptly. Our case
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Tang et al. (2012) conducted a case report in Pulmonary embolism (n=1). Low-molecular-weight heparin in combination with warfarin was evaluated on Clinical symptom resolution. Administration of low-molecular-weight heparin in combination with warfarin led to gradual subsidence of clinical symptoms in a 61-year-old man with massive pulmonary embolism.
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