A Rare Case of Raised Alkaline Phosphatase - Polyostotic Fibrous Dysplasia

Fibrous dysplasia is an uncommon, bone development abnormality characterized by the replacement of normal cancellous bone by fibrous tissue and immature woven bone. Classified according to the number of affected bones, fibrous dysplasia can affect any bones of the skeletal system, with long bones the most commonly documented site of involvement. Typically, diagnosis is based on clinical, radiological and histological findings. However, due to its broad clinical spectrum, it remains a therapeutic challenge with the efficacy of various treatment approaches still highly debated. We present a case of a polyostotic form of fibrous dysplasia in a 36-year-old Indian gentleman.