Exercise may confer cardioprotection via a direct vascular conditioning effect on the vascular wall, rather than solely through the modification of traditional risk factors.
Does exercise confer cardioprotection via direct vascular conditioning effects beyond traditional risk factor modification?
The paper proposes a paradigm shift in understanding exercise-induced cardioprotection, suggesting direct vascular conditioning effects rather than solely traditional risk factor modification.
Although it is generally accepted that the promotion of exercise accords with clinical best practice, the anecdotal experience of many primary care physicians, cardiologists, and exercise physiologists is that, even when exercise prescriptions are adhered to, risk factors often fail to demonstrate marked improvement. Since modification of traditional risk factors fails to fully explain the magnitude of exercise-mediated risk reduction (18), we propose that there are direct effects of exercise on the vascular wall, which confer cardioprotection via a "vascular conditioning" effect.
Green et al. (Thu,) conducted a review in Cardiovascular risk. Exercise was evaluated. Exercise may confer cardioprotection via a direct vascular conditioning effect on the vascular wall, rather than solely through the modification of traditional risk factors.