Key result
Variability analysis provides a novel technology to evaluate the overall properties of complex biological systems, with altered variability consistently associated with illness severity and prognosis.
Design
Review
Authors
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Variability analysis may refine ICU risk assessment; leaves open its therapeutic role pending prospective validation.
Variability analysis of physiological signals, such as heart rate variability, provides valuable prognostic information regarding the severity of illness and systemic stability in critically ill patients.
Seely et al. (2004) conducted a review in Critical illness. Variability analysis was evaluated. Variability analysis provides a novel technology to evaluate the overall properties of complex biological systems, with altered variability consistently associated with illness severity and prognosis.
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