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Case report demonstrates improvement in ventriculitis outcomes using continuous vancomycin irrigation in a patient, suggesting a promising treatment approach.
BACKGROUND: Ventriculitis usually occurs as the result of infection and results in the inflammation of the ependymal lining of the ventricular system. Mortality rates remain high despite treatment. CASE DESCRIPTION: We present the case of a 66-year-old man who presented with altered mental status and progressively became comatose. He was found to have fulminant ventriculitis due to a ruptured intracranial abscess. He was treated with bilateral IRRAflow® catheter (IRRAS, Stockholm, Sweden) placement through which continuous irrigation with vancomycin was initiated. CONCLUSION: This treatment was safe and led to improvement in the patient's neurologic examination, imaging findings, and cerebrospinal fluid profiles.
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Hess et al. (2021) studied this question.
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