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Mutations in the ZMYND11 gene impair human cortical progenitor and neuron production by disrupting both chromatin regulation and brain-specific RNA splicing, contributing to the pathogenesis of neurodevelopmental disorders. Novelty: ClaimNovelty.NOVEL_FINDING. Consensus alignment: ConsensusAlignment.NEUTRAL.

ZMYND11 functions in bimodal regulation of latent genes and brain-like splicing to safeguard corticogenesis

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