Key result
Maternal cardiovascular risk factors are linked to higher rates of adverse neonatal outcomes.
Why the study?
Cardiovascular diseases are a leading cause of mortality and morbidity worldwide, and pregnancy imposes unique physiological changes on the cardiovascular system.
Does maternal cardiovascular risk affect neonatal outcomes (gestational weeks at delivery, birth weight, and Apgar scores) in pregnant women undergoing cesarean section?
Cohort (n=68)
No
Does maternal cardiovascular risk affect neonatal outcomes (gestational weeks at delivery, birth weight, and Apgar scores) in pregnant women undergoing cesarean section?
Maternal cardiovascular risk appears to be a potential determinant of neonatal outcomes in pregnant women.
May warrant closer neonatal monitoring in cesarean deliveries with maternal CV risks; hypothesis-generating, needs prospective confirmation.
BACKGROUND: Cardiovascular diseases are a leading cause of mortality and morbidity worldwide. Pregnancy imposes unique physiological changes on a woman's cardiovascular system. MATERIALS AND METHODS: A cohort of 68 participants, comprising 30 pregnant women with cardiovascular risk and 38 without cardiovascular risk, was recruited for this study. These participants were prospectively followed during their pregnancies from 2020 to 2022 at the Obstetrics and Gynecology Department of the "Pius Brînzeu" Emergency County Clinical Hospital in Timişoara, Romania. All women included in this study underwent cesarean section deliveries at the same medical facility. Data regarding the gestational weeks at delivery, birth weight, and Apgar scores assessed by neonatologists were collected for each participant. Statistical analyses were performed to compare the neonatal effects between the two groups. CONCLUSION: The findings underscore the importance of considering maternal cardiovascular health as a potential determinant of neonatal outcomes. Further research is needed to elucidate the underlying mechanisms and develop strategies for optimizing neonatal outcomes in high-risk pregnancies.
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Abu-Awwad et al. (2023) conducted a cohort in Pregnancy with cardiovascular risk factors (n=68). Cardiovascular risk factors vs. Low-risk (absence of cardiovascular risk factors) was evaluated on Neonatal outcomes (Apgar score, birth weight, and gestational weeks) (p=0.0392). Pregnant women with cardiovascular risk factors had a higher incidence of adverse neonatal outcomes, including premature birth and lower Apgar scores, compared to low-risk women (p=0.0392).
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