Key result
Late stage heart failure (NYHA Class III or IV) was significantly associated with overactive bladder compared to no urinary symptoms (OR 2.9; 95% CI 1.344-6.250).
Cross-Sectional (n=408)
Odds Ratio: 2.9 (95% CI 1.344–6.25)
Urinary incontinence and overactive bladder are highly prevalent in heart failure patients and are associated with more severe heart failure (NYHA class III/IV) and higher BMI, but notably not with diuretic use.
PURPOSE: We explored the nature of the relationship between heart failure and urinary symptoms, specifically urinary incontinence and overactive bladder. MATERIALS AND METHODS: An 81-item written survey about urinary incontinence, urgency, frequency, nocturia and other symptoms was administered to hospitalized and clinic patients with heart failure. A medical records review was also conducted to determine types of medications, body mass index and documentation of the New York Heart Association Classification of heart failure. RESULTS: Of 408 respondents 296 (average age 62.2 years) had information about heart failure stage and urinary symptoms. Of these respondents 45% and 57% reported urinary incontinence and overactive bladder, respectively. Adjusted odds ratio for having overactive bladder over no symptoms for respondents with New York Heart Association Class III or Class IV heart failure was 2.9 (95% CI 1.344-6.250) and for higher fatigue-depression composite was 2.155 (95% CI 1.206-3.860). Adjusted odds ratio for having overactive bladder over frequency/nocturia for respondents with higher body mass index was 1.458 (95% CI 1.087-1.953) and for higher fatigue-depression composite was 1.629 (95% CI 1.038-2.550). CONCLUSIONS: Urinary incontinence and overactive bladder are prevalent in patients with heart failure. Evidence of late stage heart failure, higher fatigue-depression composite and higher body mass index were associated with overactive bladder. Sex, age and diuretic use were not associated with urinary incontinence and overactive bladder.
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Palmer et al. (2009) conducted a cross-sectional in Heart failure (n=408). New York Heart Association Class III or Class IV heart failure vs. Lower stage heart failure was evaluated on Overactive bladder (OR 2.9, 95% CI 1.344-6.250). Late stage heart failure (NYHA Class III or IV) was significantly associated with overactive bladder compared to no urinary symptoms (OR 2.9; 95% CI 1.344-6.250).
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