Key result
The PEA(area) method identified the optimal pacing configuration associated with the greatest LV dP/dt(max) in 75% (9 of 12) of CRT responders.
Why the study?
Does a peak endocardial acceleration-based algorithm accurately identify optimal CRT programming compared to invasive LV dP/dt(max) in patients with heart failure?
Does a peak endocardial acceleration-based algorithm accurately identify optimal CRT programming compared to invasive LV dP/dt(max) in patients with heart failure?
A novel peak endocardial acceleration-based algorithm shows good concordance with invasive LV dP/dt(max) for optimizing cardiac resynchronization therapy.
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PEA may aid sensor-guided CRT optimization; leaves open superiority over echo in prospective trials.
Delnoy et al. (2008) studied Heart failure (n=15). PEA(area) method vs. LV dP/dt(max) measurement was evaluated on Identification of optimal pacing configuration associated with the greatest LV dP/dt(max) among CRT responders. The PEA(area) method identified the optimal pacing configuration associated with the greatest LV dP/dt(max) in 75% (9 of 12) of CRT responders.