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August 7, 2015Stroke

Patients With Ischemic Stroke and Incident Atrial Fibrillation

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Key result

Ischemic stroke was associated with an incident atrial fibrillation rate of 7.9 per 100 person-years, compared to 5.9% in patients with a cardiac hospitalization.

Population

48,992 patients with ischemic stroke without prior diagnosed atrial fibrillation.

Design

Cohort

Follow-up

15±15 months

Authors

Laurent Fauchier
Laurent FauchierElectrophysiology
Nicolas Clémenty
Nicolas ClémentyElectrophysiology
CPChristele PeladeMedtronic (Ireland)

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Implication

Supports post-stroke AF monitoring in high-CHADS2 patients; leaves open whether screening improves outcomes.

Study Design

Type

Cohort (n=48,992)

Multicenter

Yes

Structured PICO

P
Population
48,992 patients with ischemic stroke without prior diagnosed atrial fibrillation from a French national database, followed for a mean of 15 months.
C
Comparator
826,416 patients with a cardiac hospitalization
O
Outcome
Subsequent diagnosis of atrial fibrillation (incident AF)hard clinical

Main Result

Absolute Event Rate: 7.9% vs 5.9%

Patients with ischemic stroke have a high rate of incident atrial fibrillation, which can be predicted using standard CHADS2 and CHA2DS2-VASc scores.

Cite This Study

Fauchier et al. (2015) conducted a cohort in Ischemic stroke without prior diagnosed atrial fibrillation (n=48,992). Ischemic stroke vs. Cardiac hospitalization was evaluated on Incident atrial fibrillation. Ischemic stroke was associated with an incident atrial fibrillation rate of 7.9 per 100 person-years, compared to 5.9% in patients with a cardiac hospitalization.

synapsesocial.com/papers/6a6a5dc356128ae23fcb20d9https://doi.org/10.1161/strokeaha.115.010270

Topics

Atrial fibrillationPersistent AF managementAnticoagulation in AF
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Also Consider

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  1. 1Prediction of stroke or TIA in patients without atrial fibrillation using CHADS<sub>2</sub> and CHA<sub>2</sub>DS<sub>2</sub>-VASc scores2014 · 162 citations
  2. 2Incidence of and Risk Factors for Atrial Fibrillation in Older Adults1997 · 1,471 citations
  3. 3Ischaemic cardiovascular mortality in patients with non-valvular atrial fibrillation according to CHADS2 score2011 · 22 citations
  4. 4Refining Clinical Risk Stratification for Predicting Stroke and Thromboembolism in Atrial Fibrillation Using a Novel Risk Factor-Based Approach2009 · 6,818 citations
  5. 52012 focused update of the ESC Guidelines for the management of atrial fibrillation2012 · 3,827 citations