Key result
Metabolic syndrome and its components are linked to sperm dysfunction and impaired male reproductive health.
Review examines the effects of metabolic syndrome components on male fertility, suggesting lifestyle changes for improvement.
Metabolic syndrome (MetS) represents a cluster of conditions that have a negative impact on human health overall. Its prevalence has been rapidly increasing worldwide and has coincided with a global decrease in birth rates and fertility potential. This review aims to address this observation through studying the relationship between MetS and male reproductive health. The effects of obesity, dyslipidemia, hypertension, and insulin resistance on male fertility were examined and supporting evidence explaining the pathophysiology of sperm dysfunction with each MetS component were described. Adopting a healthy lifestyle appears to be the single most important intervention to prevent the unwanted effects of MetS on men's health and fertility. Further studies addressing the components of MetS and their impact on male reproduction are required to enhance our understanding of the underlying pathophysiology and to propose new methods for therapeutic intervention.
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Martins et al. (2018) conducted a review in Metabolic syndrome and male fertility. Metabolic syndrome was evaluated on Male reproductive health and sperm dysfunction. Metabolic syndrome and its components (obesity, dyslipidemia, hypertension, and insulin resistance) are associated with sperm dysfunction and negatively impact male reproductive health.
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