Key result
Lateral transmission of force was impaired in muscles of mdx-dystrophic mice and very old rats compared to normal skeletal muscles, correlating with the loss of dystrophin expression.
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This commentary highlights novel experimental data demonstrating that lateral force transmission is impaired in dystrophic and aged mammalian muscles, though methodological concerns remain.
K. W. Ranatunga (2011) conducted an editorial in Muscular dystrophy and aging (animal models). Lateral force measurement using a yoke apparatus vs. Normal skeletal muscles (wild mice and young rats) was evaluated on Lateral transmission of force. Lateral transmission of force was impaired in muscles of mdx-dystrophic mice and very old rats compared to normal skeletal muscles, correlating with the loss of dystrophin expression.
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