What question did this study set out to answer?

To evaluate the effectiveness of supplemental 3D automated breast ultrasonography with screening mammography in detecting breast cancer in women with dense breast tissue.

October 20, 2014Radiology

Assessing Improvement in Detection of Breast Cancer with Three-dimensional Automated Breast US in Women with Dense Breast Tissue: The SomoInsight Study

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Authors

RBRachel F. BremGeorge Washington University LTLàszló TabárUppsala University SDStephen W. DuffyAstraZeneca (United Kingdom)

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Implication

Observational multicenter trial shows enhanced cancer detection in women with dense breasts, implying better screening outcomes.

Key Points

To evaluate the effectiveness of supplemental 3D automated breast ultrasonography with screening mammography in detecting breast cancer in women with dense breast tissue.
Multicenter observational study conducted from 2009 to 2011 with 15,318 women aged 25-94 years.
Participants underwent screening mammography followed by automated breast ultrasound, with results interpreted sequentially.
Follow-up was conducted for 1 year, and McNemar test assessed cancer detection differences.
112 breast cancers were diagnosed, with 82 detected by mammography and an additional 30 by AB US.
AB US resulted in an additional cancer detection rate of 1.9 per 1000 women screened (95% CI: 1.2, 2.7; P < .001).
Sensitivity increased by 26.7% (95% CI: 18.3%, 35.1%), with a recall rate increase of 284.9 per 1000 women screened (P < .001).

Cite This Study

Brem et al. (2014) studied this question.

synapsesocial.com/papers/6a6a69d3050bc01bbbcb282c https://doi.org/10.1148/radiol.14132832

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Assessing Improvement in Detection of Breast Cancer with Three-dimensional Automated Breast US in Women with Dense Breast Tissue: The SomoInsight Study

Discussion

Member takes

Implication

Key Points

Cite This Study

Assessing Improvement in Detection of Breast Cancer with Three-dimensional Automated Breast US in Women with Dense Breast Tissue: The SomoInsight Study

Discussion

Member takes

Implication

Key Points

Cite This Study

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