Key result
Cardiovascular medications were responsible for approximately 20% of medication harm overall, and up to 50% in older adults, consistently ranking among the top causes of harm.
Why the study?
Cardiovascular medications are a leading cause of harm but appear to receive less recognition as high risk medications compared with those classified by the APINCH acronym.
Do cardiovascular medications cause significant medication harm compared to other medication classes in adults?
Population
Adult (>16 years) medication harm literature across 75 studies
Comparison
Cardiovascular medications vs other medication classes
Design
Narrative review
Authors
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CV medications lead harm yet lack high-risk status; leaves open whether expanding classifications beyond APINCH improves prevention.
Do cardiovascular medications cause significant medication harm compared to other medication classes in adults?
Cardiovascular medications are a leading cause of medication harm, particularly in older adults, highlighting the need to formally recognize them as high-risk medications in clinical guidelines.
Paradissis et al. (2021) conducted a review in Medication harm (n=75). Cardiovascular medications vs. Other medication classes was evaluated on Incidence of medication harm. Cardiovascular medications were responsible for approximately 20% of medication harm overall, and up to 50% in older adults, consistently ranking among the top causes of harm.
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