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This study aims to explore the direct embryotoxic effects of aflatoxin B1 using a zebrafish model.

Embryonic exposure to low concentrations of aflatoxin B1 triggers global transcriptomic changes, defective yolk lipid mobilization, abnormal gastrointestinal tract development and inflammation in zebrafish

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This study aims to explore the direct embryotoxic effects of aflatoxin B1 using a zebrafish model.
Combined toxicological, transcriptomic, immunological, and biochemical approaches
Investigated gene expression changes in zebrafish embryos exposed to aflatoxin B1
Analyzed effects on gastrointestinal development and lipid mobilization
Increased expression of inflammatory genes and repression of lipid metabolism-related genes observed
Defective gastrointestinal tract development and massive neutrophil influx noted in exposed larvae
Reduced L-arginine levels and abnormal yolk lipid accumulation detected.

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Randomized trial examines aflatoxin B1's impact on embryonic development in zebrafish, indicating significant toxicity effects.

Ivánovics et al. (2021) studied this question.

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