Key result
A history of stroke was not associated with an increased risk of atrial fibrillation recurrence after radiofrequency catheter ablation compared to patients without a history of stroke.
Why the study?
The clinical safety and efficacy of radiofrequency catheter ablation for atrial fibrillation patients with a history of stroke needed evaluation.
Is radiofrequency catheter ablation safe and effective in atrial fibrillation patients with a history of stroke compared to those without?
Cohort (n=348)
No
Is radiofrequency catheter ablation safe and effective in atrial fibrillation patients with a history of stroke compared to those without?
Radiofrequency ablation for atrial fibrillation appears safe and effective even in patients who experienced a stroke within the previous 3 months, with similar recurrence and complication rates to those without prior stroke.
Answers are grounded in this paper and cite their sources.
May support ablation in AF patients with prior stroke; leaves open need for RCTs to confirm safety and efficacy.
Objectives: To evaluate the clinical safety and efficacy of radiofrequency catheter ablation for atrial fibrillation patients with a history of stroke. Methods and Results: A total of 116 symptomatic, drug-refractory AF patients with a history of stroke, and 1:2 matched patients without a history of stroke were enrolled. Of these, 28 cases occurred stroke within 3 months (Group 1), 88 cases with stroke history longer than 3 months (Group 2), and 232 cases without stroke (Group 3). PVI was performed in all patients, extended to ablation of linear lesions ablation. The periprocedural stroke rates and other procedure-related in-hospital complications did not differ significantly among the three groups. The maintenance rate of SR after the procedure showed no significant difference ( p = 0.333), 52.7, 66.4, and 70.7% in Group 1, 2, and 3, respectively. Furthermore, the comparison between a history of stroke and those without it were also shown no significant difference ( p = 0.351). Conclusions: Radiofrequency ablation for AF patients occurred stroke, even within 3 months is safe and effective, without higher periprocedural complication rate and recurrence rate.
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Song et al. (2021) conducted a cohort in Atrial fibrillation with a history of stroke (n=348). History of stroke vs. No history of stroke was evaluated on Recurrence of atrial fibrillation and atrial tachyarrhythmia (HR 1.023, 95% CI 0.562-1.862, p=0.941). A history of stroke was not associated with an increased risk of atrial fibrillation recurrence after radiofrequency catheter ablation compared to patients without a history of stroke.
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