The effect of different doses of aerobic exercise training on exercise blood pressure in overweight and obese postmenopausal women
Key result
Aerobic exercise training at 12 kcal/kg per week significantly reduced exercise systolic (-13.7 vs -4.2 mm Hg, P<0.001) and diastolic blood pressure compared to control in postmenopausal women.
Why the study?
Does aerobic exercise training reduce exercise blood pressure in overweight and obese postmenopausal women?
Population
404 overweight and obese postmenopausal women
Comparison
Aerobic exercise training at doses of 4, 8, or… vs Nonexercise control group
Design
RCT, randomized to one of four groups
Follow-up
6 months
Authors
Discussion
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Implication
Supports aerobic exercise at 12 kcal/kg/week to lower exercise BP in obese postmenopausal women; extends prior data with dose-response RCT evidence.
Study Design
Type
RCT (n=404)
Randomization
randomized
Structured PICO
Does aerobic exercise training reduce exercise blood pressure in overweight and obese postmenopausal women?
P
Population
404 overweight and obese postmenopausal women randomized to 4, 8, or 12 kcal/kg per week of aerobic exercise or a nonexercise control group for 6 months.
I
Intervention
Aerobic exercise training at doses of 4, 8, or 12 kcal/kg of energy expenditure per week for 6 months
C
Comparator
Nonexercise control group
O
Outcome
Exercise blood pressure (systolic and diastolic) obtained during the 50-watt stage of a cycle ergometer maximal exercise testsurrogate
Main Result
Absolute Event Rate: -13.7% vs -4.2%
p-value: p=<0.001
Aerobic exercise training effectively reduces exercise blood pressure in overweight and obese postmenopausal women, with higher doses required to significantly lower diastolic blood pressure.
Cite This Study
Swift et al. (2011) conducted an RCT in Overweight and obese postmenopausal women (n=404). Aerobic exercise training vs. Nonexercise control was evaluated on Exercise systolic blood pressure at 50 watts (p=<0.001). Aerobic exercise training at 12 kcal/kg per week significantly reduced exercise systolic (-13.7 vs -4.2 mm Hg, P<0.001) and diastolic blood pressure compared to control in postmenopausal women.