Key result
In patients aged 65-75 years with previous coronary angioplasty, the prevalence of significant (≥70%) asymptomatic internal carotid artery stenosis was low at 2.6%.
Why the study?
What is the prevalence of asymptomatic internal carotid artery stenosis in patients who have undergone previous coronary angioplasty?
Cross-Sectional (n=117)
No
What is the prevalence of asymptomatic internal carotid artery stenosis in patients who have undergone previous coronary angioplasty?
Routine screening for asymptomatic severe carotid stenosis in patients with prior coronary angioplasty has a low yield (2.6%), making its clinical utility debatable.
Screening for occult carotid stenosis may warrant consideration post-PTA; leaves open whether it improves outcomes.
OBJECTIVES: The aim was to evaluate the prevalence of asymptomatic mild (30-49%), moderate (50-69%) and severe (70-99%) ICA stenosis in patients who underwent previous coronary angioplasty (PTA). METHODS: After obtaining ethics committee approval, 144 consecutive patients aged between 65 and 75 years were invited for carotid Duplex evaluation with a linear 6 MHz array transducer by trained vascular sonographers within a single unit. A peak systolic velocity >230 cm/s in the ICA was considered as significant (>70% stenosis). RESULTS: Of the 144 patients approached, 117 (81%) attended (male:female ratio 3.2:1, age range 65-75 years, median age 71 years). Duplex ultrasound revealed one occlusion, 70% or more ICA stenosis in three patients (2.6%), 50-69% stenosis in 12 patients (10.3%) and 30-49% stenosis in 29 patients (24.8%). CONCLUSIONS: Carotid artery disease with a luminal stenosis of 30% or more is common in patients who underwent previous PTA. The yield of significant ICA stenosis (70% or more), which would benefit from carotid endarterectomy according to the Asymptomatic Carotid Surgery Trial is low. Recommendation for initial screening and subsequent follow-up Duplex examination for evaluation of disease progression of such cohorts remains debatable.
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Fassiadis et al. (2008) conducted a cross-sectional in Previous coronary angioplasty (n=117). Previous coronary angioplasty was evaluated on Prevalence of significant (>70%) internal carotid artery stenosis. In patients aged 65-75 years with previous coronary angioplasty, the prevalence of significant (≥70%) asymptomatic internal carotid artery stenosis was low at 2.6%.
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