Key result
Exercise-induced changes in carotid systolic blood pressure were significantly inversely correlated with resting midwall fractional shortening in young healthy men (r = -0.57, P = 0.011).
Why the study?
Do acute exercise-induced changes in central hemodynamics correlate with resting LV structure and function in young healthy men?
Cross-Sectional
Do acute exercise-induced changes in central hemodynamics correlate with resting LV structure and function in young healthy men?
Exercise-induced increases in central hemodynamic load correlate with lower resting LV function in young healthy men, which is not detected by traditional peripheral hemodynamics.
Central exercise BP changes associate with lower resting LV function; hypothesis-generating and should not yet change practice.
BACKGROUND: Left ventricular (LV) structure and function are predictors of cardiovascular (CV) morbidity and mortality and are related to resting peripheral haemodynamic load in older adults. The central haemodynamic response to exercise may reveal associations with LV structure and function not detected by traditional peripheral (brachial) measures in a younger population. PURPOSE: To examine correlations between acute exercise-induced changes in central artery stiffness and wave reflections and measures of resting LV structure and function. METHODS: ) had measures of central haemodynamic load measured before/after a 30-s Wingate anaerobic test (WAT). Common carotid artery stiffness and reflected wave intensity were assessed via wave intensity analysis as a regional pulse wave velocity (PWV) and negative area (NA), respectively. Resting LV structure (LV mass) and function [midwall fractional shortening (mFS)] were assessed using M-mode echocardiography in the parasternal short-axis view. RESULTS: There was a significant association between mFS and WAT-mediated change in carotid systolic BP (r = -0·57, P = 0·011), logNA (r = -0·58, P = 0·009) and PWV (r = -0·44, P = 0·045). There were no significant associations between resting mFS and changes in brachial systolic BP (r = -0·26, P>0·05). There were no associations between resting LV mass and changes in any haemodynamic variable (P>0·05). CONCLUSION: Exercise-induced increases in central haemodynamic load reveal associations with lower resting LV function in young healthy men undetected by traditional peripheral haemodynamics.
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Babcock et al. (2015) conducted a cross-sectional in Healthy. 30-s Wingate anaerobic test (WAT) vs. Traditional peripheral (brachial) haemodynamics was evaluated on Correlation between resting midwall fractional shortening (mFS) and WAT-mediated change in carotid systolic BP (r = -0.57, p=0.011). Exercise-induced changes in carotid systolic blood pressure were significantly inversely correlated with resting midwall fractional shortening in young healthy men (r = -0.57, P = 0.011).
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