Key result
Patients with atrial myxomas had significantly increased antimyolemmal antibodies compared to non-cardiac controls, with antiendothelial antibodies found in 86% of patients.
Population
Patients with endomyocardial types of cardiac tumors, Hodgkin's disease without pericarditis, pericarditis…
Design
Cross-sectional
Authors
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May indicate immune involvement in atrial myxomas; leaves open biomarker or pathogenic roles pending prospective studies.
Observational
Patients with cardiac tumors and neoplastic pericardial effusions exhibit specific cardiac autoreactive antibodies and altered local immune responses.
B Maisch (1990) conducted an observational in Cardiac tumors, Hodgkin's disease, and neoplastic pericardial effusion. Cardiac tumors and neoplastic diseases vs. Non-cardiac / healthy controls was evaluated on Presence of cardiac autoantibodies (antimyolemmal, antisarcolemmal, antiendothelial) and immune complexes. Patients with atrial myxomas had significantly increased antimyolemmal antibodies compared to non-cardiac controls, with antiendothelial antibodies found in 86% of patients.
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