Key result
The antiplatelet inhibition parameter MAADP was a significant predictor for acute thromboembolism in unruptured intracranial aneurysm patients treated by stent-assisted coiling (AUC 0.67; 95% CI 0.57-0.81; P<0.05).
Why the study?
Does thromboelastography predict acute ischemia in patients with unruptured intracranial aneurysms undergoing stent placement?
Population
46 patients with 50 unruptured intracranial aneurysms undergoing stent-assisted coiling
Design
Cohort
Follow-up
within 24 hours after treatment
Authors
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MAADP may stratify thromboembolism risk after stent-assisted coiling; hypothesis-generating for TEG-guided therapy trials.
Cohort (n=46)
Does thromboelastography predict acute ischemia in patients with unruptured intracranial aneurysms undergoing stent placement?
Effect estimate: AUC 0.67 (95% CI 0.57-0.81)
p-value: p=< 0.05
Thromboelastography parameter MAADP can predict acute thromboembolism in patients with unruptured intracranial aneurysms treated by stent-assisted coiling on dual antiplatelet therapy.
Yang et al. (2014) conducted a cohort in Unruptured intracranial aneurysm (n=46). ADP-induced clot strength (MAADP) was evaluated on Acute ischemia detected by diffusion-weighted MRI (AUC 0.67, 95% CI 0.57-0.81, p=< 0.05). The antiplatelet inhibition parameter MAADP was a significant predictor for acute thromboembolism in unruptured intracranial aneurysm patients treated by stent-assisted coiling (AUC 0.67; 95% CI 0.57-0.81; P<0.05).
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