Turkish Heart Study: lipids, lipoproteins, and apolipoproteins.
Key result
The Turkish population exhibited very low levels of HDL cholesterol (mean 34-45 mg/dl) and high total cholesterol/HDL-C ratios, representing a significant potential risk factor for heart disease.
Population
Approximately 9,000 men and women from six different regions of Turkey with markedly different diets.
Design
Cross-sectional
Authors
Discussion
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Member takes
Implication
May link olive oil-rich diets to favorable lipids; hypothesis-generating and requires prospective confirmation before practice change.
Study Design
Type
Cross-Sectional (n=9,000)
Multicenter
Yes
Structured PICO
P
Population
Approximately 9,000 men and women from six different regions of Turkey were examined to assess plasma lipids, lipoproteins, and apolipoproteins.
O
Outcome
Plasma lipids, lipoproteins, and selected apolipoproteinssurrogate
The Turkish population exhibits a distinct lipid profile characterized by strikingly low HDL cholesterol and mildly elevated triglycerides, which, combined with high smoking rates, represents a significant cardiovascular risk factor.
Cite This Study
Mahley et al. (1995) conducted a cross-sectional in General population (n=9,000). Regional and dietary differences was evaluated on Plasma lipid, lipoprotein, and apolipoprotein levels. The Turkish population exhibited very low levels of HDL cholesterol (mean 34-45 mg/dl) and high total cholesterol/HDL-C ratios, representing a significant potential risk factor for heart disease.