Key result
Analysis of 52 organisms revealed mRNA-type introns in the U6 genes of Schizosaccharomyces, Rhodotorula hasegawae, and Rhodosporidium dacryoidum, supporting a catalytic role for U6 RNA in splicing.
Population
U6 RNA genes of 52 organisms, including species of Schizosaccharomyces, Rhodotorula hasegawae, and…
Design
Preclinical
Authors
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Broadens U6 intron distribution beyond Schizosaccharomyces; leaves open evolutionary or functional implications.
The presence and specific location of mRNA-type introns in U6 RNA genes of certain yeast species support the hypothesis that U6 RNA has a catalytic role in pre-mRNA splicing.
Tani et al. (1991) studied this question. Polymerase chain reaction analysis of U6 RNA genes was evaluated on Presence and location of mRNA-type introns in U6 genes. Analysis of 52 organisms revealed mRNA-type introns in the U6 genes of Schizosaccharomyces, Rhodotorula hasegawae, and Rhodosporidium dacryoidum, supporting a catalytic role for U6 RNA in splicing.
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