What question did this study set out to answer?

This research examines the problems associated with using 'optimal' cutpoints in evaluating prognostic factors.

June 1, 1994JNCI Journal of the National Cancer Institute

Dangers of Using "Optimal" Cutpoints in the Evaluation of Prognostic Factors

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This research examines the problems associated with using 'optimal' cutpoints in evaluating prognostic factors.
Analysis of statistical methods used to determine optimal cutpoints
Review of existing literature on prognostic evaluation
Identification of potential pitfalls and misinterpretations
Using optimal cutpoints can lead to misleading conclusions about prognostic relevance
Issues of overfitting and generalizability arise when selecting cutpoints
Advocates for standardized approaches to enhance interpretability of prognostic factors

Implication

Analysis reveals issues with optimal cutpoints for prognostic factors, suggesting caution in interpretations.

Abstract

Douglas G. Altman, Berthold Lausen, Willi Sauerbrei, Martin Schumacher; Dangers of Using “Optimal” Cutpoints in the Evaluation of Prognostic Factors, JNCI: Jour

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Altman et al. (1994) studied this question.

synapsesocial.com/papers/6a6ae592d1b337d10db3884d https://doi.org/10.1093/jnci/86.11.829

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Implication

Analysis reveals issues with optimal cutpoints for prognostic factors, suggesting caution in interpretations.

Abstract

Douglas G. Altman, Berthold Lausen, Willi Sauerbrei, Martin Schumacher; Dangers of Using “Optimal” Cutpoints in the Evaluation of Prognostic Factors, JNCI: Jour

Dangers of Using "Optimal" Cutpoints in the Evaluation of Prognostic Factors

Key Points

Implication

Abstract

Discussion

Cite This Study

Dangers of Using "Optimal" Cutpoints in the Evaluation of Prognostic Factors

Key Points

Implication

Abstract

Discussion

Cite This Study

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