Key result
A standardized protocol of programmed stimulation induced sustained arrhythmias in 89% of patients with previous MI and documented VF/VT compared to 0% of controls.
Why the study?
Does a standardized protocol of programmed stimulation accurately identify predisposition to spontaneous ventricular fibrillation and tachycardia in patients with previous myocardial infarction?
Population
138 subjects, comprising 111 control subjects without ventricular disease and no history of ventricular…
Comparison
Standardized protocol of programmed stimulation… vs Control subjects without ventricular disease and…
Design
Case-control
Authors
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May aid post-MI VF/VT risk stratification; hypothesis-generating and requires prospective validation before clinical adoption.
Case-Control (n=138)
Does a standardized protocol of programmed stimulation accurately identify predisposition to spontaneous ventricular fibrillation and tachycardia in patients with previous myocardial infarction?
Absolute Event Rate: 89% vs 0%
A standardized programmed ventricular stimulation protocol is highly sensitive and specific for identifying patients predisposed to spontaneous sustained ventricular arrhythmias.
Richards et al. (1983) conducted a case-control in Predisposition to spontaneous ventricular fibrillation and tachycardia (n=138). Programmed stimulation protocol vs. Control subjects without ventricular disease and no history of VF/VT was evaluated on Induction of sustained ventricular fibrillation or tachycardia. A standardized protocol of programmed stimulation induced sustained arrhythmias in 89% of patients with previous MI and documented VF/VT compared to 0% of controls.
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