Key result
Induction of ventricular tachycardia during programmed ventricular stimulation was the only useful index for identifying high-risk patients, occurring in 81% of those with complex arrhythmias on Holter.
Why the study?
Does programmed ventricular stimulation accurately identify high-risk patients with ventricular arrhythmias compared to 24-hour ambulatory ECG?
Observational (n=75)
Does programmed ventricular stimulation accurately identify high-risk patients with ventricular arrhythmias compared to 24-hour ambulatory ECG?
Only the induction of ventricular tachycardia during programmed stimulation, rather than repetitive ventricular responses, is a useful index for identifying high-risk patients.
Answers are grounded in this paper and cite their sources.
Supports programmed ventricular stimulation for risk stratification in ventricular arrhythmias; leaves open validation versus Holter in prospective cohorts.
UNLABELLED: The study was performed to determine the predictive value of programmed stimulation for identification of pts with ventricular arrhythmias: 75 patients were studied by means of 24-hour ambulatory ECG (24 ECG) and programmed right (in some patients also left) ventricle stimulation at sinus and two or three pacing rates using two (standard) and three extrastimuli or burst stimulation (extensive protocol). Lown classes 0, 1-3 and 4a-4b were observed in 24 ECG in 35, 14, and 26 patients, respectively. In programmed stimulation 1-6 repetitive ventricular responses (RVR) were found in 56 pts, nonsustained ventricular tachycardia in 11 and sustained ventricular tachycardia in 21 pts. High incidence of induced VT was found in pts with complex ventricular arrhythmia in 24 ECG, 81% of this group, in all but six pts only standard protocol was used. The 1-6 RVR were observed in almost 40% of pts without any arrhythmia. CONCLUSION: Only VT induction is a useful index for high risk patients.
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Wnuk-Wojnar et al. (1988) conducted an observational in Ventricular arrhythmias (n=75). Programmed ventricular stimulation vs. 24-hour ambulatory ECG was evaluated on Predictive value for identification of patients with ventricular arrhythmias. Induction of ventricular tachycardia during programmed ventricular stimulation was the only useful index for identifying high-risk patients, occurring in 81% of those with complex arrhythmias on Holter.
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