Key result
Mental stress induced by mental arithmetic increased new information produced by respiratory signals and enhanced brain subnetwork connectivity compared to resting wakefulness.
Population
18 subjects
Comparison
Resting wakefulness vs mental stress (mental arithmetic) vs sustained attention (serious game)
Design
Physiological network analysis study
Authors
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Exploratory network physiology metrics during mental stress are hypothesis-generating; prospective validation needed before clinical use.
Observational (n=18)
Information dynamics analysis reveals state-dependent topology of brain-heart-respiratory networks during different levels of mental stress.
Zanetti et al. (2019) conducted an observational in Mental stress (n=18). Mental stress (mental arithmetic and serious game) vs. Resting wakefulness was evaluated on Network activity and connectivity (information dynamics). Mental stress induced by mental arithmetic increased new information produced by respiratory signals and enhanced brain subnetwork connectivity compared to resting wakefulness.