Purpose: This study evaluated the impact of magnetoencephalography-magnetic source imaging (MEG-MSI) on the presurgical evaluation of patients with epilepsy.Methods: We retrospectively analyzed presurgical evaluation reports for 64 patients considered for epilepsy surgery at a single pediatric epilepsy center.Results: Overall, 52 of 64 patients (81%) were considered candidates for resective surgery before MEG-MSI.In 37 of these 52 patients (71%), MEG-MSI findings were concordant with those of other modalities, supporting the clinical decision to proceed with resective surgery.However, in 11 of the 52 cases (21%), resective surgery was no longer considered beneficial after MEG-MSI.Among these 11 patients, five underwent either corpus callosotomy or vagus nerve stimulator insertion.Conclusion: Since MEG was incorporated into routine presurgical evaluation for patients with epilepsy, MEG-MSI findings have influenced clinical decision-making in 11 patients.
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