Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
July 30, 2026Science of Traditional Chinese MedicineOpen Access

Multicomponent tracking and targeting strategy based on ion identity molecular networking for in vivo characterization of Weifuchun constituents

View Full Paper
Ask AI
Bookmark
Share

Authors

QHQiannan HuYHYutong HuaCWChaofa Wei

Discussion

Loading...

Member takes

Overview

Randomized trial demonstrates efficient tracking of herbal components in a chronic gastritis model, indicating a novel approach to TCM research.

Key Points

  • To develop a strategy for the in vivo tracking of components in Traditional Chinese Medicine (TCM).
  • Integrated multicomponent tracking and targeting strategy developed using ion identity molecular networking.
  • Analyzed constituents of Weifuchun using ultra-high-performance liquid chromatography-electrospray ionization-Orbitrap-mass spectrometry.
  • Characterized organ-specific distribution patterns of identified components in a rat model of chronic atrophic gastritis.
  • Identified a total of 296 chemical constituents from Weifuchun.
  • Detected components absorbed into blood and their distribution across multiple tissues in rats.
  • The method provided insights into the multi-organ therapeutic effects of TCM.

Cite This Study

Hu et al. (2026) studied this question.

synapsesocial.com/papers/6a6af58c60e2b924d3ea1fe8https://doi.org/10.1097/st9.0000000000000135
View Full Paper
Ask AI
Bookmark
Share