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This study aims to identify symptom and functional clusters among stroke patients and their associated factors.

July 30, 2026HealthcareOpen Access

Symptom and Functional Clusters Regarding Patient-Reported Outcome Measures and Associated Factors Among Patients with Stroke: A Multicenter Cross-Sectional Study

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This study aims to identify symptom and functional clusters among stroke patients and their associated factors.
Cross-sectional study with 779 stroke patients from three Chinese tertiary hospitals
Electronic questionnaire covering demographics and various patient-reported outcomes
Statistical analyses including latent class analysis and multinomial logistic regression
Three symptom-functional clusters identified: low-symptom high-function (36.4%), moderate-symptom moderate-function (54.6%), high-symptom low-function (9.0%)
Factors associated with high-symptom low-function included age ≥ 60 (OR = 0.15, p = 0.001) and unemployment (OR = 2.73, p = 0.018)
High symptom burden was linked to socio-economic vulnerabilities and social isolation

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Multicenter cross-sectional study identifies symptom clusters in stroke patients, suggesting targeted management strategies for high-risk groups.

Huang et al. (2026) studied this question.

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Multicenter cross-sectional study identifies symptom clusters in stroke patients, suggesting targeted management strategies for high-risk groups.