Key result
Previous hypertensive pregnancies were not significantly associated with an increased risk of coronary artery disease compared to normotensive pregnancies (OR 1.21; 95% CI 0.64-2.28).
Why the study?
Does a history of hypertensive pregnancy increase the risk of angiographically significant coronary artery disease in parous women?
Population
217 parous women, aged 60.9±9.2 years, who required coronary angiography between January 2006 and December…
Comparison
History of ≥1 hypertensive pregnancy (HP) vs History of normotensive pregnancies
Design
Cohort
Follow-up
36.8±9.9 years after first pregnancy
Authors
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May warrant closer CAD surveillance in affected women; leaves open need for prospective screening trials.
Observational (n=217)
Does a history of hypertensive pregnancy increase the risk of angiographically significant coronary artery disease in parous women?
Odds Ratio: 1.21 (95% CI 0.64–2.28)
Women with a history of hypertensive pregnancies present with coronary artery disease at an earlier age, likely driven by intermediate cardiovascular risk factors.
Valdés et al. (2009) conducted an observational in Coronary artery disease (n=217). Hypertensive pregnancies vs. Normotensive pregnancies was evaluated on Coronary artery disease (OR 1.21, 95% CI 0.64 to 2.28). Previous hypertensive pregnancies were not significantly associated with an increased risk of coronary artery disease compared to normotensive pregnancies (OR 1.21; 95% CI 0.64-2.28).
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