A method is described for continuous recording of gastric concentrations in the normal rat. Fasting concentrations normally show a cyclical behavior with a period of 15–20 minutes. These concentrations are inhibited by instillation of many substances into the stomach via a permanent gastric fistula, the duration of the inhibition varying with volume and concentration. Neither glucose nor insulin given i.v. affects the fasting contractions; however, 0.1 mg of intravenous glucagon invariably produces complete inhibition of contractions for 4–7 minutes.
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Morrison et al. (1958) studied this question.
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