Key result
Mental stress significantly increased muscle sympathetic nerve activity (from 3.1 to 10.9 bursts/min, p<0.01) even during sustained baroreceptor stimulation with phenylephrine.
Why the study?
Does mental stress increase sympathetic nerve activity during sustained baroreceptor stimulation with phenylephrine in healthy men?
Population
9 healthy men (age range, 20-26 years)
Comparison
4-minute mental arithmetic task performed during… vs 4-minute mental arithmetic task performed before…
Design
Other
Authors
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Mental stress overrides baroreflex suppression of sympathetic activity; leaves open its role in stress-related hypertension.
Does mental stress increase sympathetic nerve activity during sustained baroreceptor stimulation with phenylephrine in healthy men?
Absolute Event Rate: 10.9% vs 3.1%
p-value: p=<0.01
Mental stress produces sympathoexcitatory and pressor responses that can override the suppressive effects of sustained arterial baroreceptor stimulation.
Anderson et al. (1991) studied Healthy (n=9). Mental stress (mental arithmetic task) vs. Resting state was evaluated on Muscle sympathetic nerve activity (MSNA) during phenylephrine infusion (p=<0.01). Mental stress significantly increased muscle sympathetic nerve activity (from 3.1 to 10.9 bursts/min, p<0.01) even during sustained baroreceptor stimulation with phenylephrine.
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