Key result
Cyclic oxygen desaturation episodes in patients with coronary artery disease were associated with marked increases in very low and low frequency power, and the low-to-high frequency ratio (P<0.01).
Why the study?
Do cyclic oxygen desaturation episodes alter heart rate variability in patients with coronary artery disease?
Population
48 patients with coronary artery disease scheduled for coronary bypass surgery, stratified by LVEF.
Comparison
Cyclic oxygen desaturation episodes vs Control episodes with normal oxygen saturation
Design
Cross-sectional
Follow-up
nocturnal recording
Authors
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Should not yet change CAD management; leaves open whether desaturation-linked HRV shifts predict outcomes or merit intervention.
Observational (n=48)
Do cyclic oxygen desaturation episodes alter heart rate variability in patients with coronary artery disease?
p-value: p=<0.01
Nocturnal repetitive oxygen desaturation episodes in CAD patients are associated with marked changes in heart rate variability, indicating cardiac sympathetic predominance, with differences based on left ventricular function.
Keyl et al. (1996) conducted an observational in Coronary artery disease (n=48). Cyclic oxygen desaturation episodes vs. Control episodes with normal oxygen saturation was evaluated on Heart rate variability (very low frequency power, low frequency power, and low-to-high frequency ratio) (p=<0.01). Cyclic oxygen desaturation episodes in patients with coronary artery disease were associated with marked increases in very low and low frequency power, and the low-to-high frequency ratio (P<0.01).
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