Key result
Early complete resolution of ST-segment elevation correlated with a higher myocardial salvage index compared to no resolution (0.54 vs 0.33, P=0.008) in patients with AMI after reperfusion therapy.
Why the study?
Does early resolution of ST-segment elevation correlate with myocardial salvage in patients with AMI after reperfusion therapy?
Population
243 patients with acute myocardial infarction treated with either coronary stenting or thrombolysis
Design
Cohort
Follow-up
6 months
Authors
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Supports ECG as noninvasive salvage marker post-AMI reperfusion; extends scintigraphic correlations but leaves open prospective outcome validation.
Cohort (n=243)
Does early resolution of ST-segment elevation correlate with myocardial salvage in patients with AMI after reperfusion therapy?
Absolute Event Rate: 0.54% vs 0.33%
p-value: p=0.008
Early resolution of ST-segment elevation on surface ECG correlates with myocardial salvage assessed by scintigraphy and predicts final infarct size and 6-month mortality in patients with AMI after reperfusion therapy.
Dong et al. (2002) conducted a cohort in Acute myocardial infarction (n=243). Early resolution of ST-segment elevation vs. Partial or no resolution was evaluated on Myocardial salvage index (p=0.008). Early complete resolution of ST-segment elevation correlated with a higher myocardial salvage index compared to no resolution (0.54 vs 0.33, P=0.008) in patients with AMI after reperfusion therapy.
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