Key result
In older patients undergoing elective abdominal surgery, dementia (OR 3.52; 95% CI 1.35-9.20) and kidney disease (OR 1.64; 95% CI 1.04-2.57) were independent risk factors for 30-day mortality.
Why the study?
Comorbidities may cause perioperative complications and impact outcomes in older patients, prompting this study to analyse comorbidity burdens and their predictive power in elderly patients undergoing elective or emergency abdominal surgery.
Does comorbidity burden predict 30-day mortality and morbidity in older patients undergoing abdominal emergency or elective surgery?
Observational (n=1,586)
No
Does comorbidity burden predict 30-day mortality and morbidity in older patients undergoing abdominal emergency or elective surgery?
Odds Ratio: 3.52 (95% CI 1.35–9.2)
In older patients undergoing elective abdominal surgery, specific comorbidities such as dementia and kidney disease predict 30-day mortality, whereas heart disease predicts 30-day major morbidity.
May aid preoperative risk stratification in elective cases; leaves open whether interventions modify outcomes.
BACKGROUND: Comorbidities may cause complications in perioperative care and affect treatment outcomes of older patients. The study aim was to analyse comorbidity burdens with respect to their predictive power in outcome prediction in elderly qualified for abdominal elective or emergency surgery. METHODS: Consecutive patients undergoing major abdominal surgery between 2010 and 2017 at a secondary referral hospital were included in the retrospective study, for a total of 1586 patients. To explain the relationship between the comorbidity types and 30-day mortality and morbidity logistic regression analysis was performed. Morbidity was assessed using the Clavien-Dindo Score. Major complications were defined as a C-D score ≥ 3. We also presented the data concerning need for reoperation and ICU admission. RESULTS: 85.9% of patients had at least one comorbidity. In the group of emergency patients age and number of comorbidities were independent risk factors of 30-day mortality and major morbidity. In elective patients age, dementia (OR:3.52; 95%CI:1.35-9.20) and kidney disease (OR:1.64; 95%CI:1.04-2.57) were found to be independent risk factors of 30-day postoperative mortality. Age (1.04; 95%CI:1.00-1.08) and heart disease (OR:1.30, 95%CI:1.04-1.63) were found to be independent risk factors of 30-day major morbidity. CONCLUSIONS: In patients undergoing elective surgery 30-day mortality and morbidity was associated with age. 30-day mortality, but not morbidity was associated with kidney disease and dementia. 30-day morbidity, but not mortality, was associated with heart disease.
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Skorus et al. (2020) conducted an observational in Major abdominal surgery (n=1,586). Comorbidity burden (e.g., dementia, kidney disease, heart disease) was evaluated on 30-day postoperative mortality (OR 3.52, 95% CI 1.35-9.20). In older patients undergoing elective abdominal surgery, dementia (OR 3.52; 95% CI 1.35-9.20) and kidney disease (OR 1.64; 95% CI 1.04-2.57) were independent risk factors for 30-day mortality.
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