Key result
Positive-strand RNA virus genome replication occurs inside virus-induced vesicles derived from a continuous membrane network, often closely associated with sites of virion assembly and budding.
Population
Positive-strand RNA viruses
Design
Review
Authors
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3D tomography clarifies conserved replication factory ultrastructure across RNA viruses; leaves open functional and therapeutic validation.
This review highlights common structural principles of positive-strand RNA virus replication factories, providing insights into the organization and coordination of virus replication.
Boon et al. (2010) conducted a review in Positive-strand RNA virus infection. Positive-strand RNA virus genome replication occurs inside virus-induced vesicles derived from a continuous membrane network, often closely associated with sites of virion assembly and budding.
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