Key result
A one-point increment in the simplified thrombo-inflammatory score (sTIPS) was associated with a 51% increase in the risk of in-hospital death and an 89% increase in long-term mortality.
Why the study?
Does a higher simplified thrombo-inflammatory score (sTIPS) predict increased mortality in diabetic patients with STEMI?
Cohort (n=465)
Does a higher simplified thrombo-inflammatory score (sTIPS) predict increased mortality in diabetic patients with STEMI?
Effect estimate: 51% increase (in-hospital) and 89% increase (long-term) in risk per 1-point increment
The novel simplified thrombo-inflammatory score (sTIPS) is a useful prognostic tool for predicting short- and long-term mortality in diabetic patients presenting with STEMI.
Aim: We investigated prognostic value of novel simplified thrombo-inflammatory score (sTIPS) in patients with ST-elevation myocardial infarction (STEMI) and diabetes mellitus. Methods: A total of 465 patients with diabetes mellitus and STEMI were included in the study. Based on admission cut-off values for predicting in-hospital mortality of white blood cell count (>13.4 × 103/mm3) and mean platelet volume-to-platelet count ratio (>0.06), the patients were assigned 0 point for having the lower value of each variable and 1 point for having the upper value of each variable. sTIPS was calculated as the sum of these two variables. Results: Kaplan–Meier curves demonstrated that higher sTIPS categories were associated with higher in-hospital and 12-month mortality. One-point increment in the score was associated with 51% increase in the risk of in-hospital death and 89% increase in the risk of long term. Conclusion: sTIPS is useful in predicting worse immediate and long-term outcomes following STEMI.
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Hudzik et al. (2016) conducted a cohort in ST-elevation myocardial infarction (STEMI) and diabetes mellitus (n=465). Simplified thrombo-inflammatory score (sTIPS) vs. Lower sTIPS categories was evaluated on In-hospital and 12-month mortality (51% increase (in-hospital) and 89% increase (long-term) in risk per 1-point increment). A one-point increment in the simplified thrombo-inflammatory score (sTIPS) was associated with a 51% increase in the risk of in-hospital death and an 89% increase in long-term mortality.
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