Key result
An increased platelet-release reaction after myocardial infarction was significantly associated with death within a year compared to controls (P<0.01) and surviving patients (P=0.02).
Why the study?
Does the platelet-release reaction correlate with prognosis in patients with myocardial infarction?
Population
26 patients (22 definite and 4 possible myocardial infarction) and 54 age-matched controls
Comparison
Measurement of platelet-release reaction in… vs Age-matched controls
Design
Cohort
Follow-up
1 year
Authors
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May identify high-risk post-MI patients; leaves open whether platelet reactivity is modifiable or causal.
Case-Control (n=80)
Does the platelet-release reaction correlate with prognosis in patients with myocardial infarction?
p-value: p=<0.01
An increased platelet-release reaction after myocardial infarction is associated with a poor prognosis and higher 1-year mortality.
Heptinstall et al. (1980) conducted a case-control in Myocardial infarction (n=80). Myocardial infarction vs. Age-matched controls was evaluated on Platelet-release reaction (p=<0.01). An increased platelet-release reaction after myocardial infarction was significantly associated with death within a year compared to controls (P<0.01) and surviving patients (P=0.02).
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